Sacha Zeerleder Selected Research

Nucleosomes (Nucleosome)

1/2019	The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion.
12/2017	DNA and factor VII-activating protease protect against the cytotoxicity of histones.
10/2017	Neutrophil extracellular traps in patients with pulmonary tuberculosis.
12/2016	Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation.
3/2016	FSAP-mediated nucleosome release from late apoptotic cells is inhibited by autoantibodies present in SLE.
8/2015	Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia.
1/2015	Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos.
12/2014	Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis).
2/2014	Nucleosomes in individuals with hip fracture with and without delirium.
11/2013	Nucleosomes and neutrophil activation in sickle cell disease painful crisis.

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Sacha Zeerleder Research Topics

Disease

17	Sepsis (Septicemia) 11/2018 - 07/2003
14	Inflammation (Inflammations) 01/2021 - 07/2003
6	Infections 02/2022 - 12/2014
6	Pneumonia (Pneumonitis) 11/2018 - 03/2011
6	Septic Shock (Toxic Shock Syndrome) 01/2011 - 07/2003
5	Hereditary Angioedemas 01/2021 - 08/2008
5	Neoplasms (Cancer) 01/2020 - 01/2006
5	Myocardial Infarction 01/2017 - 01/2006
4	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 11/2021 - 02/2013
4	Thrombosis (Thrombus) 11/2021 - 09/2006
4	Hemolysis 11/2021 - 01/2014
4	Wounds and Injuries (Trauma) 01/2021 - 03/2012
4	Angioedema 01/2019 - 11/2015
4	Myocarditis (Carditis) 01/2017 - 12/2014
3	Necrosis 01/2021 - 03/2011
3	Disseminated Intravascular Coagulation 01/2016 - 08/2005
2	Anemia 02/2022 - 11/2021
2	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 11/2021 - 01/2018
2	Burns 01/2021 - 07/2012
2	Lung Injury 12/2020 - 12/2016
2	Critical Illness (Critically Ill) 12/2020 - 01/2006
2	Acquired angioedema 01/2019 - 11/2015
2	Edema (Dropsy) 01/2016 - 06/2011
1	Hemostatic Disorders 02/2022
1	Blood Platelet Disorders (Thrombocytopathy) 02/2022
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2022
1	Reperfusion Injury 10/2021
1	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2021
1	Ventilator-Induced Lung Injury 12/2020
1	Cytokine Release Syndrome 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020
1	Hemolytic Anemia 11/2019
1	Communicable Diseases (Infectious Diseases) 11/2019
1	Malaria 11/2019
1	Ischemia 01/2019
1	Atypical Hemolytic Uremic Syndrome 01/2018
1	Tuberculosis (Tuberculoses) 10/2017
1	Pulmonary Tuberculosis 10/2017
1	Factor XI Deficiency (Hemophilia C) 02/2017
1	Asthma (Bronchial Asthma) 01/2017
1	Pericarditis 08/2016

Drug/Important Bio-Agent (IBA)

16	Complement System Proteins (Complement)IBA 11/2021 - 07/2003
16	Nucleosomes (Nucleosome)IBA 01/2019 - 07/2003
4	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2021 - 07/2012
4	CytokinesIBA 01/2019 - 07/2003
4	Histones (Histone)IBA 12/2017 - 12/2012
4	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 01/2011
4	Protein CIBA 07/2013 - 10/2005
3	Proteins (Proteins, Gene)FDA Link 12/2017 - 08/2015
3	Leukocyte Elastase (Neutrophil Elastase)IBA 10/2017 - 12/2014
3	AutoantibodiesIBA 11/2015 - 01/2014
3	lipoprotein-associated coagulation inhibitor (TFPI)IBA 02/2015 - 10/2005
3	Interleukin-8 (Interleukin 8)IBA 01/2015 - 07/2003
3	AntigensIBA 01/2014 - 01/2006
3	AntithrombinsIBA 10/2012 - 10/2005
2	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2020
2	Hemoglobins (Hemoglobin)IBA 11/2021 - 01/2014
2	Complement Inactivating AgentsIBA 01/2021 - 11/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 10/2012
2	Cell-Free Nucleic AcidsIBA 12/2019 - 01/2006
2	Fibrinolysin FDA Link 01/2019 - 01/2006
2	Hemostatics (Antihemorrhagics)IBA 01/2019 - 08/2005
2	VaccinesIBA 01/2019 - 02/2015
2	DNA (Deoxyribonucleic Acid)IBA 12/2017 - 12/2016
2	Factor XII (Hageman Factor)IBA 02/2017 - 01/2017
2	Colchicine FDA LinkGeneric 01/2017 - 08/2016
2	BradykininIBA 01/2016 - 01/2016
2	Dacarbazine (DIC)FDA LinkGeneric 01/2016 - 09/2006
2	Peptides (Polypeptides)IBA 01/2016 - 06/2011
2	AntibodiesIBA 11/2015 - 01/2014
2	Factor VII (Proconvertin)IBA 03/2012 - 01/2011
2	Plasminogen InactivatorsIBA 01/2006 - 01/2006
1	Biological ProductsIBA 11/2021
1	Heme (Haem)IBA 11/2021
1	Blood Proteins (Serum Proteins)IBA 01/2021
1	Complement C4 (Complement Component 4)IBA 01/2021
1	InterleukinsIBA 01/2020
1	mitoquinoneIBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 01/2019
1	Transaminases (Aminotransferases)IBA 01/2019
1	AntioxidantsIBA 01/2019
1	Rituximab (Mabthera)FDA Link 01/2019
1	PlasminogenIBA 01/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	Antisense OligonucleotidesIBA 11/2018
1	Pancreatic Elastase (Elastase)IBA 10/2017
1	AllergensIBA 02/2017
1	Factor XI (Plasma Thromboplastin Antecedent)IBA 01/2017
1	KininsIBA 01/2017
1	ChromatinIBA 12/2016
1	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 12/2016
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2016
1	Pharmaceutical PreparationsIBA 08/2016

Therapy/Procedure

7	Therapeutics 02/2022 - 07/2003
2	Hematopoietic Stem Cell Transplantation 02/2022 - 01/2019
1	Transplantation 10/2021
1	Mechanical Ventilators (Ventilator) 12/2020
1	Artificial Respiration (Mechanical Ventilation) 12/2020
1	Stem Cell Transplantation 01/2017